US FDA Lifts Partial Clinical Hold on Karyopharm’s Selinexor Clinical Trials

When there is so much that is negative in the news, it is great to be able to report today that myeloma clinical trials with selinexor (KPT-330) can again move forward.

Extra p53 genes in elephants prevent cancer: how about for myeloma patients?

A recent provocative report by Lisa Abegglen and a team from the Huntsman Cancer Institute in Salt Lake City, Utah showed that elephants from the San Diego Zoo had 20 extra copies of the p53 gene. Since p53 is a tumor suppressor gene, the researchers linked this to the low occurrence of cancer in these elephants, even in old age. So, is this correlation correct?