Recharging Resilience on Vacation and Finding Earth’s Home in the Universe

While on vacation for 2019, I am recharging my resilience for the coming months. I have a photo to share with the myeloma patients who created the “Wall of Resilience,” a collage of inspirational images displayed this summer at the IMF’s annual Support Group Leaders Summit. Like many of these patients, I too draw strength from the natural beauty in the world that persists, despite threats from all sides.

New Drug Combinations Show Promising Results, an Orphan Drug Designation, and the FDA Speeds International Approvals

The phase III CANDOR clinical trial has met its primary endpoint, according to a Sept. 13 announcement by Amgen. The endpoint was improved progression-free survival (PFS), which was 15.8 months for the doublet of Kyprolis+dexamethasone versus the triplet of Kyprolis+Darzalex+dexamethasone (D-Kd), for which the PFS was not yet reached. This represented a 37% reduction in risk of relapse or death in this population of patients with relapsed/refractory myeloma.

New Drug Updates: GSK Announces Positive Results from anti-BCMA Immune Conjugate Trial

On August 23, GlaxoSmithKline announced positive headline results for the DREAMM-2 randomized trial with two doses of GSK2857916 (belantamab mafodotin or “Bela”), an anti-BCMA monoclonal antibody drug conjugate. (View IMF video about belantamab mafodotin, filmed at ASCO 2019.) Exact responses and outcomes were not disclosed, but excellent results were previously reported. Safety and tolerability were acceptable, as noted in the earlier DREAMM-1 exploratory study. 

Real Food: Critically Important for the World’s Health

I have written a lot about the benefits of “real food,” especially as part of a Mediterranean-style diet. A large new study reaffirms the benefits of a Mediterranean diet and links the global burden of disease to a poor diet.

Remembering a myeloma patient advocate extraordinaire

With great sorrow we announce the passing of Aldo Del Col, M.S.M., Co-Founder of Myeloma Canada and International Myeloma Foundation Board of Directors Member.