With the placement of two more checkpoint inhibitor combination trials on partial hold, the US Food and Drug Administration (FDA) has now halted all such trials from four different pharmaceutical companies: Merck, Bristol-Myers Squibb, Celgene, and now Roche. Roche and its subsidiary Genentech announced that the agency has placed a partial hold on two trials that combine atezolizumab (Tecentriq®) with lenalidomide (Revlimid®) or pomalidomide (Pomalyst®) to treat relapsed/refractory multiple myeloma.