CAR T-Cell Therapy Results Reported in The New England Journal of Medicine

Submitted by blackswan on Fri, 05/10/2019 - 22:29

This week it is exciting to see the results of CAR T-cell therapy reported fully in The New England Journal of Medicine (NEJM). Results using the bb2121 anti-BCMA CAR T-cells were reported previously in abstract form at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting. But the NEJM article provides important details about safety (the primary endpoint for this phase I study), as well as the anti-myeloma activity of the CAR T-cells directed against the BCMA (B-cell maturation antigen) on the myeloma cells of the relapsed/refractory-treated patients.